发明名称 |
PYRAZOLOPYRIMIDINE DERIVATIVE |
摘要 |
<p>[PROBLEMS] To provide a novel compound capable of inhibiting the activity of HSP90, particularly a novel compound capable of inhibiting the chaperon protein function of HSP90 and having an anti-tumor activity. [MEANS FOR SOLVING PROBLEMS] A pyrazolopyrimidine compound represented by the formula (1) having various substituents, which is capable of inhibiting the ATPase activity of HSP90 and has an anti-tumor activity; an HSP90 inhibitor comprising the compound represented by the formula (1); a pharmaceutical agent comprising the compound represented by the formula (1); an anti-cancer agent comprising the compound represented by the formula (1); a pharmaceutical composition comprising the compound represented by the formula (1); a method for the treatment of cancer by using the compound represented by the formula (1); and others. (1)</p> |
申请公布号 |
KR20090066274(A) |
申请公布日期 |
2009.06.23 |
申请号 |
KR20097005525 |
申请日期 |
2007.09.14 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
OHSUKI SATORU;TENGEIJI ATSUSHI;IKEDA MASAHIRO;SHIBATA YOSHIHIRO;NAGATA CHIKAHIRO;SHIMADA TAKASHI |
分类号 |
C07D495/22;A61K31/519;A61P43/00;C07D498/22 |
主分类号 |
C07D495/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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