发明名称 NEW INDOLE DERIVATIVES WITH 5-HT6 RECEPTOR AFFINITY
摘要 This invention relates to compounds which have generally 5-HT6 receptor affinity and which are represented by Formula (I), wherein one of R5, R6 or R7 is a group of general Formula (B), wherein W is a -CH- group or a nitrogen atom, and the other substituents are as defined herein; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, their use as therapeutic agents, and methods of preparation thereof. (see formula I) (see formula B)
申请公布号 CA2449874(C) 申请公布日期 2009.06.23
申请号 CA20022449874 申请日期 2002.05.29
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BEARD, COLIN CHARLES;CLARK, ROBIN DOUGLAS;FISHER, LAWRENCE EMERSON;HARRIS, RALPH NEW III;REPKE, DAVID BRUCE
分类号 C07D403/04;A61K;A61K31/405;A61K31/4523;A61K31/454;A61K31/496;A61P;A61P1/04;A61P3/04;A61P21/04;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P43/00;C07D;C07D209/30;C07D401/04;C07D401/12;C07D401/14;C07D417/14 主分类号 C07D403/04
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