发明名称 Photosensitizer and method for production thereof
摘要 The invention relates to medicine and concerns a photosensitizer for detecting and curing tumors. The inventive photosensitizer is embodied in the form of a composition containing chlorin in the form of salt and alkali metals. The chlorin is composed of 80-90% of chlorin e6, 5-20 of purpurin 5 and the rest being purpurin 18-chlorin p6. Said photosensitizer is produced by extracting Spirulina biomass with the aid of acetone. Afterwards said biomass is exposed to acid treatment, neutralization, hydrolysis, extraction of pheophorbide a, dissolution in acetone, addition of a strong base, neutralization and reprecipitation of chlorin e6.
申请公布号 US7550587(B2) 申请公布日期 2009.06.23
申请号 US20050171076 申请日期 2005.06.30
申请人 OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIJU "RADA-PHARMA" 发明人 RESHETNIKOV ANDREI VALENTINOVICH;ZALEVSKY IGOR DMITRIEVICH;KEMOV JURY VIKTOROVICH;IVANOV ANDREI VALENTINOVICH;KARMENYAN ARTASHES VACHEEVICH;GRADJUSHKO ALEXANDR TIKHONOVICH;LAPTEV VLADIMIR PETROVICH;NEUGODOVA NATALIYA PETROVNA;ABAKUMOVA OLGA YURIEVNA;PRIVALOV VALERY ALEXEEVICH;LAPPA ALEXANDR VLADIMIROVICH;ROMANOV VLADIMIR ALEXANDROVICH
分类号 A61K31/409;C07B47/00;A61K41/00;A61K49/00;A61P35/00;C07D487/22 主分类号 A61K31/409
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