NOVEL COMPOUNDS ISOLATED FROM KOREAN BLACK RASPBERRY WINE AND THEIR ISOLATION METHODS

摘要

Three kinds of novel materials isolated from Rubus coreanum Miquel wine is provided to detect various physiological activity and be used as a lead compound of food and medicinal and pharmaceutical agent. Three kinds of novel material isolated from Rubus coreanum Miquel wine comprises a rubuate A, rubuate B, and rububenzoside. The rubuate A is obtained by solvent fraction and normal phase column. The rubuate B is obtained by solvent fraction to produce ethylacetate fraction, column chromatography of silica gel and sephadex LH-20 and reverse phase HPLC(high performance liquid chromatography) The rububenzoside is obtained by solvent fraction to produce butanol fraction, column chromatography of amberlite XAD-2, sepadex LH-20 and ODS and reverse phase HPLC.