发明名称 HIGH-LIPID PLAQUE STABILISATION METHOD AND METHOD OF DESTRUCTION PREVENTION
摘要 FIELD: medicine. ^ SUBSTANCE: atherosclerotic plaques are stabilised by introduction of effective amount of 2-[4-[2-(benzimidazole-2-ylthio)ethyl]piperazine-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamide, or the pharmaceutical composition containing effective amount of this compound as an active principle. ^ EFFECT: effective prevention of plaque destruction, their stabilisation ensured by reduced amount of macrophages and increased collagen fibres in atherosclerotic plaques. ^ 12 cl, 7 dwg, 1 ex
申请公布号 RU2358734(C2) 申请公布日期 2009.06.20
申请号 RU20060110035 申请日期 2004.08.19
申请人 KOVA KO., LTD. 发明人 SIBUJA KIMIJUKI;KOBAJASI KHIDEJUKI;JOSINAKA JASUNOBU
分类号 A61K31/4439;A61P9/10;C07D401/12 主分类号 A61K31/4439
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