发明名称 EPOTHILONE DERIVATIVE FOR TREATMENT OF HEPATOME AND OTHER CANCER DISEASES
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to medical products, particularly to application of compound of formula I where A stands for O, R stands for hydrogen or lower alkyl, and Z stands for O to prepare a medicinal agent for treatment of cancer disease chosen from primary cancer of Fallopian tube; primary peritoneal cancer and colorectal cancer progressing after Irinotecan therapy. Besides the invention concerns the pharmaceutical composition including specified compound, therapy of specified diseases and commercial package. formula (I). ^ EFFECT: agent is characterised with improved effectiveness. ^ 13 cl, 7 ex
申请公布号 RU2358730(C2) 申请公布日期 2009.06.20
申请号 RU20040135307 申请日期 2003.04.30
申请人 NOVARTIS AG 发明人 ROTERMEL DZHON DEJVID
分类号 C07D277/24;A61K31/425;A61K31/426;A61K31/427;A61K41/00;A61K45/06;A61P35/00;A61P35/04 主分类号 C07D277/24
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