发明名称 METHOD FOR MAKING TICK-BORNE ENCEPHALITIS DIAGNOSTICUM
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to medicine and veterinary science. The method involves ultrasonic machining of virus-containing suspensions of various, including avid, tick-borne encephalitis virus strains. The ultrasonic machining is characterised with frequency 22 kHz, duration 1 min and performed three times every two min with an apparatus UZDN-1 or UZDN-A. Method allows improving diagnostic effectiveness of the prepared preparation manifested in increased titres detected in bloods serum of infected antibodies, diagnostic increases of antibody titres in hemagglutination inhibition reaction and reliability of confirmation rate of clinical diagnosis "tick-borne encephalitis" to 33%. ^ EFFECT: invention can be used in making diagnostic preparations and in improving clinical effectiveness of serum diagnostics of tick-borne encephalitis. ^ 2 cl, 4 tbl, 3 ex
申请公布号 RU2359269(C2) 申请公布日期 2009.06.20
申请号 RU20070130140 申请日期 2007.08.06
申请人 FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE NAUKI EKATERINBURGSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT VIRUSNYKH INFEKTSIJ (FGUN ENIIVI) 发明人 KOKOREV VALERIJ SERAFIMOVICH;KIRSANOV JURIJ ALEKSANDROVICH;KRZHIZHANOVSKAJA OL'GA ALEKSANDROVNA
分类号 G01N33/531 主分类号 G01N33/531
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