USE OF AN IONIC COMPLEX OF GENTAMICIN : AOT FOR THE TREATMENT OF BRUCELLOSIS

摘要

The invention relates to an ionic complex of gentamicin and sodium bis(2-ethylhexyl) sulfosuccinate (AOT) in a molar ratio of 1:5 (gentamicin : AOT) for the production of a drug intended for the treatment of a disease caused by a bacterium of the genus Brucella. In one embodiment of the invention, the therapeutic ionic complex is also treated by: (a) dissolving the gentamicin : AOT ionic complex in an organic solvent; (b) spraying the solution resulting from step (a) into a compressed fluid miscible with the organic solvent, which acts as an antisolvent and causes the precipitation of a solid; and (c) separating the solid resulting from step (b).