发明名称 |
LACTAM COMPOUND OR SALT THEREOF, AND PPAR ACTIVATOR |
摘要 |
<p>Disclosed is a compound having a lactam skeleton or a salt thereof, which is useful as a PPAR activator. Specifically disclosed is a lactam compound represented by formula (1) or a salt thereof. (1) wherein R1 represents a halogen, a hydrocarbon group, a carboxyl group or the like; Z1 represents an arene ring or a hetero ring; Z3 represents an alicyclic or aromatic hydrocarbon ring; Z2 represents a 5- to 6-membered ring containing a nitrogen atom; X1 represents a C, O, S or N atom, a group -N-C(=O)- or a group -C(=O)-N-; R2 represents a hydrogen atom or an alkyl group which may have a substituent; R3 and R4 independently represents a single bond or a bivalent aliphatic hydrocarbon group, provided that at least one of R3 and R4 represents an aliphatic hydrocarbon group; X2 and X3 independently represent a single bond, an O or S atom, an imino group or the like; A1 represents a single bond or a phenylene group which may have a substituent; Y1 represents a hydrogen atom, a halogen atom, a carboxyl group or the like; a represents an integer of 0 to 5; b represents an integer of 0 to 2; and c represents an integer of 1 to 3.</p> |
申请公布号 |
WO2009072581(A1) |
申请公布日期 |
2009.06.11 |
申请号 |
WO2008JP72094 |
申请日期 |
2008.12.04 |
申请人 |
ASKA PHARMACEUTICAL CO., LTD.;AOTSUKA, TOMOJI;KANAZAWA, HASHIME;KUMAZAWA, KENTAROU |
发明人 |
AOTSUKA, TOMOJI;KANAZAWA, HASHIME;KUMAZAWA, KENTAROU |
分类号 |
C07D209/46;A61K31/4035;A61K31/4439;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P43/00;C07D401/04;C07D409/10 |
主分类号 |
C07D209/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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