摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for synthesizing and producing N-substituted maleimides. <P>SOLUTION: The present invention provides the method for producing and synthesizing an N-substituted maleimides in an organic solvent that is azeotropic with water, and in the presence of a supported catalyst where an organic phosphonic acid having a melting point higher than 150°C and insoluble with the N-substituted maleimide is carried on a solid carrier, a primary amine and maleic anhydride are administered to carried out the cyclodehydration at 100 to 140°C. According to this invention, a method for producing the N-substituted maleimides of high purity in high yield is provided. <P>COPYRIGHT: (C)2009,JPO&INPIT |