4-OXO-(ISO)TRETINOIN FOR THE TOPICAL TREATMENT OF SEVERE DERMATOLOGICAL DISORDERS

摘要

A method for the treatment of dermatological disorders wherein such treatment includes at least one of inhibiting lipogenesis in the skin and reducing the size of sebaceous glands, said treatment comprising the topical administration of a compound selected from 4-oxo-tretinoin, 4-oxo-isotretinoin and mixtures thereof to a patient in need thereof. The method of the invention is particularly advantageous for the topical treatment of severe acne and seborrhoea.