FUNCTIONAL ASSAY FOR INDENTIFICATION OF LOSS-OF-FUNCTION MUTATIONS IN GENES
摘要
<p>Provided herein are compositions and methods for assaying the deleteriousness of putative loss-of-function mutations, especially in genes known to be or suspected of being tumor-suppressor genes. The invention includes syngeneic variance libraries and methods of construction and use of syngeneic variance libraries.</p>
申请公布号
WO2009032185(A3)
申请公布日期
2009.06.11
申请号
WO2008US10233
申请日期
2008.08.28
申请人
THE JOHNS HOPKINS UNIVERSITY;KERN, SCOTT, E.;GALLMIER, EIKE;HUCL, TOMAS
