| 摘要 |
A composition for preventing and treating liver disease is provided to ensure the effects of DNA fragmentation suppression, caspase-3 and caspase-8 activity inhibition, poly(ADP-ribose)polymerase inhibition and JNK phosphorylation inhibition. A composition for treating and preventing liver disease comprises an oroxylin A of the chemical formula A as an active ingredient. The oroxylin A suppresses the liver cell damage by bilestagnation. The liver disease is selected from autoimmunity liver disease, drug attractancy liver disease, adrenoleukodystrophy, infection liver disease, congenital metabolic liver disease, bile congestion, acute hepatitis, permanent exposure, cirrhosis, steatosis or liver cancer. The composition is contained in a ratio of 0.1-50 weight% based on total weight. A health functional food containing the oroxylin A for preventing liver disease and improving cure thereof is used in a form of powder, granule, tablet, capsule and beverage.
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