The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
申请公布号
WO2008150897(A3)
申请公布日期
2009.06.11
申请号
WO2008US65130
申请日期
2008.05.29
申请人
UNIVERSITY OF IOWA RESEARCH FOUNDATION;DAVIDSON, BEVERLY, L.;MAS MONTEYS, ALEJANDRO;MCBRIDE, JODI, L.;BOUDREAU, RYAN
发明人
DAVIDSON, BEVERLY, L.;MAS MONTEYS, ALEJANDRO;MCBRIDE, JODI, L.;BOUDREAU, RYAN