| 发明名称 |
METHODS FOR DETERMINING THE ACTIVITY OF ADAM-TS PROTEASES USING THIOPEPTOLIDES |
| 摘要 |
The invention concerns the use of thiopeptolides of formula R-(Xaa)n-Pro-X-Gly-S-Y-Z-Gly-(Xaa)m-R1 (I) as substrate for determining the activity of ADAMTS proteases, and a method for finding an ADAMTS protease modulator, more particularly an inhibitor.
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| 申请公布号 |
US2009149332(A1) |
申请公布日期 |
2009.06.11 |
| 申请号 |
US20060814936 |
申请日期 |
2006.02.10 |
| 申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
WEITHMANN KLAUS-ULRICH;JESKE VOLKER |
| 分类号 |
C40B30/00;C12Q1/37 |
主分类号 |
C40B30/00 |
| 代理机构 |
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