发明名称 |
METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE a-METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L-META-TYROSINE AND THE a |
摘要 |
The invention relates to a method for producing precursors for L-2-[18F]fluorophenylalanine and 6-[18F]fluoro-L-meta-tyrosine and the a-methylated derivatives thereof, said precursor, and a method for producing L-2-[18F]fluorophenylalanine and 2-[18F]fluoro-L-meta-tyrosine and the a-methylated derivatives thereof from the precursor. According to the invention, a compound of formula (3) is used to enable an automated synthesis of L-3,4-dihydroxy-6-[18F]fluorophenylalanine and 6-[18F]fluoro-L-meta-tyrosine. The enantiomer purity of the product amounts to = 98%. |
申请公布号 |
WO2009071050(A2) |
申请公布日期 |
2009.06.11 |
申请号 |
WO2008DE01936 |
申请日期 |
2008.11.21 |
申请人 |
FORSCHUNGSZENTRUM JUELICH GMBH;WAGNER, FRANZISKA;ERMERT, JOHANNES;COENEN, HEINRICH, HUBERT |
发明人 |
WAGNER, FRANZISKA;ERMERT, JOHANNES;COENEN, HEINRICH, HUBERT |
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