发明名称 |
ELEVATION OF THE PLASMA HDL-CHOLESTEROL LEVEL |
摘要 |
<p>The present invention relates to the use of isosteviol, steviol, and related compounds for elevating the plasma HDL-cholesterol level. The invention furthermore relates to the use of these compounds for reducing the body weight of a subject and/or lowering the plasma triglyceride level of a subject, including a concomitant elevation of the plasma HDL-cholesterol level. Preferably the compounds used are isosteviol and/or steviol, or pharmaceutically acceptable salts, solvates or prodrugs thereof. The compounds may furthermore be administered in combination with one or more further active compounds, such as e.g. LDL-cholesterol lowering agents. The invention furthermore relates to a method for elevating the plasma HDL-cholesterol level in a subject by administering to a subject in need of such treatment a plasma HDL-cholesterol level elevating amount of the compounds, described herein.</p> |
申请公布号 |
WO2009071099(A1) |
申请公布日期 |
2009.06.11 |
申请号 |
WO2008DK50297 |
申请日期 |
2008.12.05 |
申请人 |
AARHUS UNIVERSITET;HERMANSEN, KJELD;JEPPESEN, PER BENDIX |
发明人 |
HERMANSEN, KJELD;JEPPESEN, PER BENDIX |
分类号 |
A61K31/19;A61K45/06;A61P3/04 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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