| 发明名称 |
GPCR crystalization method using an antibody |
| 摘要 |
An antibody that specifically binds a three dimensional epitope on the IC3 loop of a GPCR is provided. The antibody may be employed in a method that comprises: contacting a GPCR with a monovalent version of the antibody binding conditions to form a complex; and crystallizing the complex.
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| 申请公布号 |
US2009148510(A1) |
申请公布日期 |
2009.06.11 |
| 申请号 |
US20080284245 |
申请日期 |
2008.09.19 |
| 申请人 |
KOBILKA BRIAN;ROHRER DANIEL K;BRAHMS PETER;MASOOD ASNA |
发明人 |
KOBILKA BRIAN;ROHRER DANIEL K.;BRAHMS PETER;MASOOD ASNA |
| 分类号 |
A61K9/127;A61P37/04;C07K16/00;G01N33/567 |
主分类号 |
A61K9/127 |
| 代理机构 |
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