发明名称 |
MUTATIONAL ANALYSIS OF CHRONIC MYELOPROLIFERATIVE DISORDERS |
摘要 |
The invention relates to molecular assays, reagents and kit for the mutational analysis, for diagnostic and prognostic purposes, of chronic myeloproliferative disorders, a group of neoplastic pathologies of the haemopoietic system. The invention relates to the identification of nucleic acid probes labelled with fluorochrome, allowing a quantitative assessment, in a specific and sensitive way, of mutation of MPL gene sequence and quantification of the mutated alleles of the MPL gene in Genomic DNA samples from patients with chronic myeloproliferative syndrome. |
申请公布号 |
WO2009072084(A2) |
申请公布日期 |
2009.06.11 |
申请号 |
WO2008IB55122 |
申请日期 |
2008.12.05 |
申请人 |
UNIVERSITA' DEGLI STUDI DI FIRENZE;VANNUCCHI, ALESSANDRO MARIA;PANCRAZZI, ALESSANDRO;GUGLIELMELLI, PAOLA;PONZIANI, VANESSA |
发明人 |
VANNUCCHI, ALESSANDRO MARIA;PANCRAZZI, ALESSANDRO;GUGLIELMELLI, PAOLA;PONZIANI, VANESSA |
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