PATCH SPREADED ON THE AFFECTED PART, ELIMINATED USING COLD WATER, WITHOUT FABRIC

摘要

A patch without non-woven fabric is provided, which enables the simple use for a patient having many hairs. A patch formulation uses temperature sensitive polymer for sol-gel transition. The temperature sensitive polymer is selected from poly(NIPAAM) and its derivative, PEO-PPO-PEO copolymer and its derivative, MPEG-PLGA and its derivative, PEG-PLGA-PEG copolymer and its derivative, and polyphosphazene and its derivative. The concentration of temperature sensitive polymer is 0.1-45%. The patch formulation further comprises adhesive base and excipient.