发明名称 Sequences facilitating penetration of a substance of interest
摘要 The present invention relates to an amino acid sequence being able to facilitate penetration of a substance of interest inside cells and/or cell nuclei and having the following formula (I) [(X1)p [(X)o (B)nX B X X B]m (X2)q wherein X1 and X2 are amino acid sequences of 1 to 20 amino acids; p and q are whole numbers between 0 and 5; B is a basic amino acid; X is a non-basic, preferably hydrophobic amino acid, such as alanine, isoleucine, leucine, methionine, phenylalanine, tryptophan, valine or tyrosine; n is 2 or 3; m is 1 to 4; o is 0 or 1, between 0 and 5; B is a basic amino acid; X is a non-basic, preferably hydrophobic amino acid, such as alanine, isoleucine, leucine, methionine phenylalanine, tryptophan, valine or tyrosine; n is 2 or 3; m is 1 to 4; o is 0 or 1.
申请公布号 US7544664(B2) 申请公布日期 2009.06.09
申请号 US20040568108 申请日期 2004.08.13
申请人 DIATOS, S.A. 发明人 AVRAMEAS ALEXANDRE
分类号 A61K38/00;A61K31/70;A61K31/7048;A61K38/03;A61K38/08;A61K38/10;A61K38/16;A61K45/00;A61K45/06;A61K48/00;C07K7/00;C07K7/04;C07K7/08;C07K14/00;C12N1/15;C12N5/20;C12N15/11 主分类号 A61K38/00
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