| 发明名称 |
IL-6 MUTEIN |
| 摘要 |
The present invention relates to a new IL-6 mutein, a DNA sequence coding fo r it, its use in therapy as well as a pharmaceutical composition comprising it. It is a potent IL-6 antagonist and can be advantageously used as a medicament in the treatment of diseases in which IL-6 has a pathogenetic action, such as, for example, plasmocytoma/myeloma, osteoporosis and neoplastic and autoimmune diseases.</ SDOAB>
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| 申请公布号 |
CA2251355(C) |
申请公布日期 |
2009.06.09 |
| 申请号 |
CA19962251355 |
申请日期 |
1996.04.09 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
EHLERS, MARC;ROSE-JOHN, STEFAN;GROTZINGER, JOACHIM |
| 分类号 |
C12N15/24;A61K;A61K31/00;A61K38/00;A61K38/20;A61P19/10;A61P35/00;A61P37/00;A61P43/00;C07K;C07K14/54;C12N;C12N1/21;C12N15/09;C12P21/02 |
主分类号 |
C12N15/24 |
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