发明名称 NEW AMYLOID-AFFINITIVE COMPOUND
摘要 PROBLEM TO BE SOLVED: To provide a compound which is effective as a probe for image diagnosis targeting amyloid, and to provide a reagent containing the compound and used for detecting amyloid deposited in living body tissues. SOLUTION: The compound is represented by formula, wherein, R<SP>1</SP>is a radioactive halogen substituent; (m) is an integer of 1 to 4, and the reagent containing the compound and used for detecting amyloid deposited in living body tissues. The compound has affinity to amyloid deposited in living body tissues, and has a good clearance from normal tissues. The compound can be suitably used for providing a new amyloid-affinitive compound having a good amyloid-detecting ability in living bodies, and a reagent for detecting the amyloid deposited in living body tissues. COPYRIGHT: (C)2009,JPO&amp;INPIT
申请公布号 JP2009120591(A) 申请公布日期 2009.06.04
申请号 JP20080269517 申请日期 2008.10.20
申请人 NIHON MEDI PHYSICS CO LTD 发明人 TANIFUJI SHIGEYUKI;NAKAMURA DAISAKU;TAKASAKI SHINYA;OKUMURA YUKI
分类号 C07D471/04;A61K51/00 主分类号 C07D471/04
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