发明名称 MACROCYCLIC TETRAZOLYL HEPATITIS C SERINE PROTEASE INHIBITORS
摘要 The present invention relates to compounds of Formula I, II, III or IV, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
申请公布号 US2009142299(A1) 申请公布日期 2009.06.04
申请号 US20080270963 申请日期 2008.11.14
申请人 SUN YING;LIU DONG;OR YAT SUN;WANG ZHE 发明人 SUN YING;LIU DONG;OR YAT SUN;WANG ZHE
分类号 A61K38/21;A61K38/06;A61P31/12;C07K5/12 主分类号 A61K38/21
代理机构 代理人
主权项
地址