发明名称 |
COMPOUNDS THAT INCREASE TELOMERASE REVERSE TRANSCRIPTASE (TERT) EXPRESSION AND METHODS FOR USING THE SAME |
摘要 |
Compounds, and methods of using the same, are provided which increase the expression of telomerase reverse transcriptase (TERT) in a cell. These compounds and methods find use in a variety of applications in which increased expression of telomerase is desired, including immortalization of cell lines and treating conditions in a subject characterized by cellular senescence.
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申请公布号 |
US2009143451(A1) |
申请公布日期 |
2009.06.04 |
申请号 |
US20080270552 |
申请日期 |
2008.11.13 |
申请人 |
ANDREWS WILLIAM H;BRIGGS LAURA A;FOSTER CHRISTOPHER A;BROWN LANCER K;PIATYSZEK MIECZYSLAW A;GAETA FEDERICO C A;CHAGUTURU MUNIRATHNAM;ZHANG JIAN;KERLEY TOM |
发明人 |
ANDREWS WILLIAM H.;BRIGGS LAURA A.;FOSTER CHRISTOPHER A.;BROWN LANCER K.;PIATYSZEK MIECZYSLAW A.;GAETA FEDERICO C.A.;CHAGUTURU MUNIRATHNAM;ZHANG JIAN;KERLEY TOM |
分类号 |
A61K31/422;C12N5/02;C12Q1/02 |
主分类号 |
A61K31/422 |
代理机构 |
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地址 |
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