NOVEL PEPTIDES DERIVED FROM NCAM (FGLS)

摘要

The present invention relates to novel compounds comprising at most 13 contiguous amino acid residues derived from the fibronectin type 3,Il module of neural cell adhesion molecule (NCAM), or a variant or fragment thereof, capable of interacting with an FGFR and thereby the compounds are capable of inducing differentiation, modulating proliferation, stimulate regeneration, neuronal plasticity and/or survival of cells. Further, the present invention relates to the use of said compounds for production of a medicament for treatment of conditions and diseases, wherein NCAM and/or FGFR play a prominent role.