| 发明名称 |
AMPLIFICATION OF CANCER-SPECIFIC ONCOLYTIC VIRAL INFECTION BY HISTONE DEACETYLASE INHIBITORS |
| 摘要 |
The invention provides methods for treating cancer cells in a host by infecting the cancer cells with one or more strains of oncolytic virus, in conjunction with treating the host with an amount of an HDI that is effective to augment the cancer-cell-specific oncolytic infection.
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| 申请公布号 |
CA2706750(A1) |
申请公布日期 |
2009.06.04 |
| 申请号 |
CA20082706750 |
申请日期 |
2008.11.26 |
| 申请人 |
OTTAWA HEALTH RESEARCH INSTITUTE |
发明人 |
BELL, JOHN CAMERON;HISCOTT, JOHN;ABDELBARY, HESHAM;NGUYEN, LIEN-ANH;DIALLO, JEAN-SIMON |
| 分类号 |
A61K35/76;A61K31/16;A61K31/165;A61K31/18;A61K31/19;A61K31/4353;A61K31/4406;A61P35/00 |
主分类号 |
A61K35/76 |
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