PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES

摘要

The invention relates to pyrrolidine- and piperidine-derivatives of formula (I), wherein Y represents (CH2)n; n represents 0 or 1; A represents B represents phenyl, wherein the phenyl-ring is unsubstituted or mono- or di- or tri- substituted, wherein the substituents are independently selected from the group consisting of (C1-4)alkyl, (C1-4)alkoxy, trifluoromethyl, cyano, and halogen; R1 represents an imidazothiazole-group selected from: R2 represents (C1-4)alkyl, bromine or -NH2; and R3 represents hydrogen or (C1-4)alkyl; and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.