摘要 |
<p>The present invention is based on the discovery that a single nucleotide polymorphism (SNP) present the chitinase 3-like 1 gene (CHI3L1) encoding YKL-40 or a regulatory domain of the CHI3L1 gene, is associated with elevated YKL-40 levels, as well as an increased risk for developing a lung disorder, including asthma, bronchial hyperresponsivity, and/or reduced lung function.</p> |
申请人 |
YALE UNIVERSITY;THE UNIVERSITY OF CHICAGO;CHUPP, GEOFFREY, L.;ELIAS, JACK, A.;OBER, CAROLE |
发明人 |
CHUPP, GEOFFREY, L.;ELIAS, JACK, A.;OBER, CAROLE |