发明名称 |
IL24 FOR INDUCING HYPERPROLIFERATIVE OR AUTOIMMUNE CELL DEATH |
摘要 |
The invention concerns the use of IL24 for the treatment of a hyperproliferative or autoimmune disorder by inducing death of hyperproliferative or autoimmune cells, in particular through stimulation of p53 expression. The invention also relates to a a kit comprising IL24 and a cytokine likely to trigger hyperproliferative or autoimmune cells into cell cycle as a combined preparation for sequential use for the treatment of a hyperproliferative or autoimmune disorder. The invention further provides an inhibitor of activated-Stat3 for treating chronic lymphocytic leukaemia. |
申请公布号 |
WO2009050267(A3) |
申请公布日期 |
2009.06.04 |
申请号 |
WO2008EP64040 |
申请日期 |
2008.10.17 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);DALLOUL, ALI;GARY, HELENE |
发明人 |
DALLOUL, ALI;GARY, HELENE |
分类号 |
A61K38/20;A61K31/08;A61K31/277;A61K31/427;A61K31/58;A61P35/00;A61P35/02;C07K14/16 |
主分类号 |
A61K38/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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