摘要 |
<p>The present invention provides a Compound of formula (I), wherein: R<sup>1</sup> is a group selected from -CH2OH,-NH(CO)H; and R<sup>2</sup> is a hydrogen atom; or R<sup>1</sup> together with R<sup>2</sup> form the group -NH-C(O)-CH=CH-, wherein the nitrogen atom is bound to the carbon atom in the phenyl ring holding R<sup>1 </sup>and the carbon atom is bound to the carbon atom in the phenyl ring holding R<sup>2</sup>;<sup/>R<sup>3a</sup> and R<sup>3b</sup> are independently selected from the group consisting of hydrogen atoms and C1-4 alkyl groups; X and Y are independently selected from the group consisting of direct bond and oxygen atom; n, m and q each independently has a value selected from 0, 1, 2 and 3; p has a value selected from 1, 2 and 3; R<sup>4</sup> and R<sup>5</sup> are independently selected from hydrogen atoms, halogen atoms, C1-4 alkyl, C1-4 alkoxy, -CONH2, -NHCONH2, -SR<sup>7</sup>, -SOR<sup>7</sup>, -SO2R<sup>7</sup>, -SO2NHR<sup>8</sup> and the groups (a) and (b), wherein R<sup>7</sup> is selected from C1-4alkyl and C3-8 cycloalkyl and R<sup>8</sup> is selected from hydrogen atoms and C1-4alkyl groups; R<sup>6</sup> is selected from the group consisting of hydrogen atoms, halogen atoms, C1-4 alkyl and C1-4 alkoxy or a pharmaceutically-acceptable salt, solvate or stereoisomer thereof.</p> |