| 摘要 |
A container comprising a container body defining a storage chamber for receiving a substance and a container closure removably attached to the container body for sealing the storage chamber. The container closure includes a base defining an aperture in fluid communication with the storage chamber, and a needle penetrable and thermally resealable stopper overlying the aperture for aseptically filling the storage chamber with the substance and sealing the substance within the storage chamber with respect to the ambient atmosphere. A sealing portion engages the container body prior to filling and forms a substantially dry hermetic seal between the container closure and container body. The container further comprises an over closure engageable with the container closure such that removal or movement of the over closure from a first position to a second position results in substantially simultaneous removal of the container closure and stopper to allow dispensing of the substance.
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