发明名称 OMEGA-3 LIPID COMPOUNDS
摘要 The present invention relates to compositions comprising at least omega-3 lipid compounds substituted at the 2-positions having therapeutic activity. More specifically, the present invention relates to a composition comprising at least omega-3 lipid compounds substituted at the 2-position, counted from the functional group (X) of the omega-3 lipid compound, wherein the omega-3 lipid compounds comprise: a compound of general formula (I): and a compound of formula (II): wherein R1 and R2 are the same or different and are chosen from a hydrogen atom, a hydroxy group, an alkyl group, a halogen atom, an alkoxy group, an acyloxy group, an acyl group, an alkenyl group, an alkynyl group, an aryl group, an alkylthio group, an alkoxycarbonyl group, a carboxy group, an alkylsulfinyl group, an alkylsulfonyl group, an amino group, and an alkylamino group; and X represents a carboxylic acid or a derivative thereof, a carboxylate, a carboxylic anhydride, a hydroxymethyl (-CH2OH) or a pro-drug thereof, or a carboxamide, or any pharmaceutically acceptable complex, salt, solvate, or pro-drug, with the provisos that: R1 and R2 are not simultaneously hydrogen.
申请公布号 WO2008142482(A3) 申请公布日期 2009.06.04
申请号 WO2007IB04613 申请日期 2007.11.01
申请人 PRONOVA BIOPHARMA NORGE AS;HOLMEIDE, ANNE KRISTIN;ROSMAN, JENNY 发明人 HOLMEIDE, ANNE KRISTIN;ROSMAN, JENNY
分类号 C07C33/02;A61K31/045;A61K31/047;A61K31/075;A61K31/10;A61K31/22;C07C43/178;C07C69/007;C07C69/24;C07C69/40;C07C69/587;C07C69/96;C07C309/67;C07C323/14;C07F9/113 主分类号 C07C33/02
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