发明名称 |
Microwave mediated synthesis of nucleic acid probes |
摘要 |
A method for preparing a nucleic acid probe is provided. The method comprises forming an activated cytosine or cytidine by a bisulfite catalyzed reaction; and covalently linking a reporter molecule to the activated cytosine or cytidine, wherein said activating step, said covalently linking step, or both are conducted in the presence of microwave energy. Also provided by the invention are nucleic acid probes.
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申请公布号 |
US7541455(B2) |
申请公布日期 |
2009.06.02 |
申请号 |
US20040018897 |
申请日期 |
2004.12.21 |
申请人 |
VENTANA MEDICAL SYSTEMS, INC. |
发明人 |
BIENIARZ CHRISTOPHER;FARRELL MICHAEL;KOSMEDER JEROME W.;LEFEVER MARK |
分类号 |
C07H21/02;C07H21/04;C12N13/00;C12Q1/68;C40B40/06;H05B6/64 |
主分类号 |
C07H21/02 |
代理机构 |
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主权项 |
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地址 |
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