发明名称 |
Anti-rhesus D monoclonal antibodies |
摘要 |
The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby of for uses such as idiopathic thrombocytopenic pupura (ITP).
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申请公布号 |
US7541029(B2) |
申请公布日期 |
2009.06.02 |
申请号 |
US20060517525 |
申请日期 |
2006.09.08 |
申请人 |
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES |
发明人 |
BELIARD ROLAND;BOUREL DOMINIQUE;GLACET AMAUD;ROMEUF CHRISTOPHE DE;BIHOREAU NICOLAS;NONY EMMANUEL |
分类号 |
A61K39/395;C12N15/09;A61P7/00;A61P15/00;A61P31/00;A61P35/00;A61P37/02;A61P37/06;C07K16/34;C07K17/00;C12N5/10;C12N5/20;C12N15/02;C12N15/13;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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