摘要 |
Selected heterocyclic compoundsare effective for prophylaxis and treatment o f diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds of Formula II' (shown below), analogs, prodrugs and pharmaceutical ly acceptable derivatives thereof, pharmaceutical compousitions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. (see above formula)
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申请人 |
AMGEN INC. |
发明人 |
CROGHAN, MICHAEL;BEMIS, JEAN;CAI, GUOLIN;BOOKER, SHON;DOMINGUEZ, CELIA;ELBAUM, DANIEL;PATEL, VINOD F.;SMITH, LEON M., II;GERMAIN, JULIE;GEUNS-MEYER, STEPHANIE;STEC, MARKIAN;HANDLEY, MICHAEL;OUYANG, XIAOHU;XU, SHIMIN;YUAN, CHESTER CHENGUANG;KIM, JOSEPH L.;HUANG, QI;KIM, TAE-SEONG;XI, NING;KISELYOV, ALEXANDER;ADAMS, JEFFREY;TASKER, ANDREW;DIPIETRO, LUCIAN;CHEN, GUOQING |