发明名称 |
Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one |
摘要 |
Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.
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申请公布号 |
US7541460(B2) |
申请公布日期 |
2009.06.02 |
申请号 |
US20050311194 |
申请日期 |
2005.12.19 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CHAN YEUNG YU;RIJHWANI SUSHIL K. |
分类号 |
C07D473/18;C07D473/12;C07D473/40;C07F7/08;C07F7/10;C07F7/18 |
主分类号 |
C07D473/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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