发明名称 Method for manufacturing an optically active hydroxymethylated compound and a catalyst therefore
摘要 A silicon enolate represented by the following formula (Formula 1) (in the formula, R5 to R7 represent hydrogen atoms, aliphatic hydrocarbon groups, monocyclic or polycyclic alicyclic hydrocarbon groups, monocyclic or polycyclic aromatic or aromatic-aliphatic hydrocarbon groups or heterocyclic groups, R5 and R7 are different, R6 is not a hydrogen atom, each R8 may be identical or different and represents a methyl group, ethyl group or isopropyl group) and formaldehyde are allowed to react in an aqueous solution or a mixed solvent of water and an organic solvent in the presence of a catalyst obtained by mixing a ligand comprising a chiral bipyridine compound or its antipode and Bi(OTf)3.
申请公布号 US7541307(B2) 申请公布日期 2009.06.02
申请号 US20060795525 申请日期 2006.01.27
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 KOBAYASHI SHU;MANABE KEI
分类号 B01J31/00;C07C45/00;C07C49/00 主分类号 B01J31/00
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