发明名称 METHOD FOR DIAGNOSING IMMUNE SYSTEM DISEASES AND COMPOUNDS THAT CAN BE USED TO TREAT SAID DISEASES
摘要 The invention relates to a method for the diagnosis and prognosis of a disease associated with stimulation of the immune system, based on the in vitro determination of the phosphorylation level of DGK in the Y335 tyrosine residue in cells of the immune system, as well as a specific antibody of the protein. In addition, the invention relates to nucleotides which inhibit the expression of said protein and can be used in the treatment of autoimmune diseases and cancers of the immune system.
申请公布号 WO2008148926(A3) 申请公布日期 2009.05.28
申请号 WO2008ES70111 申请日期 2008.06.04
申请人 CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSIDAD AUTONOMA DE MADRID;MERIDA SAN ROMAN, ISABEL;MERINO PLAZA, ERNESTO;SAITO, NAOKAI;SHIRIAI, YASUHITO;KAKEHI, TOMOKO;MATSUBARA, TAKEHIRO;AVILA FLORES, JUANA ANTONIA 发明人 MERIDA SAN ROMAN, ISABEL;MERINO PLAZA, ERNESTO;SAITO, NAOKAI;SHIRIAI, YASUHITO;KAKEHI, TOMOKO;MATSUBARA, TAKEHIRO;AVILA FLORES, JUANA ANTONIA
分类号 C12Q1/25;A61K39/00;G01N33/573 主分类号 C12Q1/25
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