发明名称 Substituted biphenyl GPR40 modulators
摘要 The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
申请公布号 US2009137561(A1) 申请公布日期 2009.05.28
申请号 US20080287036 申请日期 2008.10.03
申请人 AMGEN INC. 发明人 BROWN SEAN P.;CAO QIONG;DRANSFIELD PAUL JOHN;DU XIAOHUI;HOUZE JONATHAN;JIAO XIAN YUN;KIM YONG-JAE;KOHN TODD J.;LAI SUJEN;LI AN-RONG;LIN DANIEL;LUO JIAN;MEDINA JULIO C.;REAGAN JEFFREY D.;PATTAROPONG VATEE;SCHWARZ MARGRIT;SHEN WANG;SU YONGLI;SWAMINATH GAYATHRI;VIMOLRATANA MARC;WANG XIANG;XIONG YUMEI;YANG LI;YU MING;ZHANG JIE;ZHU LIUSHENG
分类号 C07C59/48;A61K31/192;A61K31/235;A61K31/351;A61K31/44;A61K31/445;A61K31/55;A61P7/00;C07C69/76;C07D211/20;C07D223/04;C07D309/00 主分类号 C07C59/48
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