发明名称 |
Inhibition of macrophage-stimulating protein receptor (RON) and methods of treatment thereof |
摘要 |
The invention provides antibodies or fragments thereof, including human antibodies, specific for Macrophage-Stimulating Protein Receptor (MSP-R or RON), which inhibit RON activation. Also provided are methods to inhibit RON, particularly the use of RON antibodies to treat diseases such as cancer.
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申请公布号 |
US2009136510(A1) |
申请公布日期 |
2009.05.28 |
申请号 |
US20080313589 |
申请日期 |
2008.11.21 |
申请人 |
IMCLONE SYSTEMS INCORPORATED |
发明人 |
PEREIRA DANIEL;O'TOOLE JENNIFER |
分类号 |
A61K39/395;C07H21/04;C07K16/00;C12N5/00;C12N15/63;C12P21/04;G01N33/53 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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