发明名称 2-AMINOQUINAZOLINE DERIVATIVES
摘要 The present invention provides 2-aminoquinazoline derivatives represented by formula (I): wherein R1 and R2 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, and the like; X represents a bond or CR7aR7b wherein R7a and R7b may be the same or different and each represents a hydrogen atom, and the like; when X is a bond, R3 represents substituted or unsubstituted aryl or a substituted or unsubstituted aromatic heterocyclic group; when X is CR7aR7b wherein R7a and R7b have the same meanings as defined above, respectively, R3 represents substituted or unsubstituted lower alkoxy, substituted or unsubstituted aryl, and the like; R4 represents a hydrogen atom, hydroxy, substituted or unsubstituted lower alkoxy, and the like; and R5 represents a hydrogen atom, substituted or unsubstituted aryl, and the like, or a pharmaceutically acceptable salt thereof.
申请公布号 US2009137583(A1) 申请公布日期 2009.05.28
申请号 US20060912679 申请日期 2006.04.28
申请人 KYOWA HAKKO KOGYO CO., LTD. 发明人 KISHIKAWA KUNIYUKI;IMASE HIDETOMO;KASHIMA HAJIME;MORI KIYOTOSHI;IKEMURA TOSHIHIDE;NAKASATO YOSHISUKE;TOMURO MISATO
分类号 A61K31/5377;A61K31/496;A61K31/517;A61K31/519;A61P29/00;C07D239/70;C07D239/72;C07D413/02 主分类号 A61K31/5377
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