A METHOD OF IMMOBILISING BIOLOGICAL MOLECULES TO A SUPPORT AND PRODUCTS THEREOF
摘要
<p>A support comprising a substrate, wherein a surface of the substrate comprises functional amino or aldehyde groups, for the covalent binding of a biomolecule. The biomolecule may be a protein such as an affinity protein. The invention also provides a method for the covalent binding of a biomolecule to a surface of a support through its amino or carboxyl group. The method comprises the steps of: providing a support substrate; cleaning a surface of a support substrate; functionalising the support substrate by chemically creating hydroxyl groups on the cleaned surface of the support substrate; inducing amines on the surface of the support substrate; and covalently binding a biomolecule to the support substrate. The biomolecule may be protein such as an affinity protein.</p>
申请公布号
WO2009066275(A1)
申请公布日期
2009.05.28
申请号
WO2008IE00112
申请日期
2008.11.24
申请人
DUBLIN CITY UNIVERSITY;SANDEEP, KUMAR, VASHIST;HARRY, HOLTHOFER;KIRK, LEISTER