发明名称 |
N-ACYLHYDRAZONE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS |
摘要 |
This invention relates to N-acylhydrazone derivatives (I), which are found to be useful as modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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申请公布号 |
WO2009065854(A1) |
申请公布日期 |
2009.05.28 |
申请号 |
WO2008EP65830 |
申请日期 |
2008.11.19 |
申请人 |
NEUROSEARCH A/S;NARDI, ANTONIO;CHRISTENSEN, JEPPE, KEJSER;PETERS, DAN;DYHRING, TINO |
发明人 |
NARDI, ANTONIO;CHRISTENSEN, JEPPE, KEJSER;PETERS, DAN;DYHRING, TINO |
分类号 |
C07D209/18;A61K31/405;A61P5/00;A61P17/00;A61P21/00;A61P25/00;A61P25/30;C07D209/30;C07D409/12 |
主分类号 |
C07D209/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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