| 发明名称 |
INHIBITORS OF CATHEPSIN S |
| 摘要 |
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
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| 申请公布号 |
US2009137570(A1) |
申请公布日期 |
2009.05.28 |
| 申请号 |
US20090361287 |
申请日期 |
2009.01.28 |
| 申请人 |
IRM LLC |
发明人 |
LIU HONG;CHATTERJEE ARNAB K.;TULLY DAVID C.;ALPER PHILLIP B.;BURSULAYA BADRY;GUO JIANHUA;WOODMANSEE DAVID H.;MUTNICK DANIEL;KARANEWSKY DONALD S.;HE YUN |
| 分类号 |
A61K31/5377;A61K;A61K31/397;A61K31/401;A61K31/404;A61K31/423;A61K31/445;A61K31/454;A61K31/495;A61K31/537;A61K31/5375;A61K31/54;A61K31/541;C07D209/04;C07D209/08;C07D241/04;C07D261/14;C07D265/30;C07D279/12;C07D295/13;C07D295/145;C07D295/18;C07D295/20;C07D401/12;C07D403/12;C07D411/12;C07D413/12;C07D413/14;C07D417/12 |
主分类号 |
A61K31/5377 |
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