发明名称 A NOVEL PROCESS FOR THE PREPARATION OF 3-AMINO-PENTAN-1,5-DIOL
摘要 The present invention provides a novel method for preparing a key intermediate, 3-amino-pentan-l,5-diol (2), which is useful for the preparation of 6-(2,4- difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H- pyrido[2,3-d]pyrimidine-7-one (1) a MAP -kinase inhibitor useful in the treatment of rheumatoid arthritis.
申请公布号 WO2008151992(A3) 申请公布日期 2009.05.28
申请号 WO2008EP57072 申请日期 2008.06.06
申请人 F. HOFFMANN-LA ROCHE AG;CLEARY, THOMAS, P.;JI, YAOHUI;LEE, GARY, R.;RAWALPALLY, THIMMA;SARMA, KESHAB 发明人 CLEARY, THOMAS, P.;JI, YAOHUI;LEE, GARY, R.;RAWALPALLY, THIMMA;SARMA, KESHAB
分类号 C07C213/02;C07C215/10;C07C269/04;C07C269/06;C07C271/16;C07C271/22 主分类号 C07C213/02
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