发明名称 |
Neuronal Network-Interacting Peptide |
摘要 |
The invention provides a method for treating a neuronal-associated condition comprising administering a composition comprising a therapeutically effective amount of a polypeptide or a biologically active fragment thereof, the polypeptide or the fragment thereof capable of modulating the interaction between Nogo-ephrinB and/or Nogo-Grb4 third SH3 domain. There are also provided isolated polypeptide or fragment thereof. The invention further provides a method of screening a compound for effectiveness as an agonist or as an antagonist of the polypeptide or fragment thereof according to the invention.
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申请公布号 |
US2009137484(A1) |
申请公布日期 |
2009.05.28 |
申请号 |
US20050791958 |
申请日期 |
2005.12.01 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE |
发明人 |
SONG JIANXING;LI MINFEN;LIU JINGXIAN;RAN XIAOYUAN |
分类号 |
A61K38/08;C07K7/00;C07K14/00;C12N1/21;C12N5/06;C12N15/00;C12N15/11;C12P21/04;C12Q1/02;G01N33/00 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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