发明名称 COMBINED METHOD OF BONE GRAFT STERILISATION
摘要 FIELD: medicine. ^ SUBSTANCE: there is disclosed method of acid demineralisation of bone graft tissue, including its preparation, mechanical treatment and demineralisation preceded with keeping the bone tissue during 24 hours at +5Ç+7C in 1% sodium chloride solution. Then it is removed from solution, frozen and like this placed in dissolved hydrochloric or hydrobromic acid of specified concentration ensuring partial or complete demineralisation of bone grafts. Invention allows for considerable (2.5 to 1.2 Mrad) reduction of radiation dose on bone tissue, providing reliable sterilising effect and keeping its high grafting properties. ^ EFFECT: two-staged combined sterilisation allows accumulating plastic material after the first stage and to sterilise it with gamma-rays as required, routinely thereby reducing number of visits to the institutions having radionuclide installations with gamma radiation source Co60. ^ 4 ex, 1 tbl, 7 dwg
申请公布号 RU2356224(C1) 申请公布日期 2009.05.27
申请号 RU20070149035 申请日期 2007.12.21
申请人 FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE "ROSSIJSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT TRAVMATOLOGII I ORTOPEDII IM. R.R. VREDENA FEDERAL'NOGO AGENTSTVA PO VYSOKOTEKHNOLOGICHNOJ MEDITSINSKOJ POMOSHCHI" (FGU "RNIITO IM. R.R. VREDENA ROSMEDTEKHNOLOGIJ 发明人 SAVEL'EV VLADIMIR IL'ICH;BULATOV ALEKSANDR ANATOL'EVICH;RYKOV JURIJ ALEKSEEVICH
分类号 A01N1/02;A61F2/28;A61L27/00 主分类号 A01N1/02
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