发明名称 |
SOLID PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING OPTICALLY STABLE RAMOSETRON |
摘要 |
Provided is a preparation of ramosetron which is stable under irradiation with light. The solid pharmaceutical composition of the present invention can provide a stable preparation by blending a compound absorbing light having a specific wavelength with ramosetron which is unstable, usually under irradiation with light, or a pharmaceutically acceptable salt thereof. Particularly, this technique is useful because it is adaptable to a preparation containing ramosetron or a pharmaceutically acceptable salt thereof at a low content or an orally disintegrating tablet containing ramosetron or a pharmaceutically acceptable salt thereof. Also, the present invention relates to a method for stabilizing a solid pharmaceutical composition of ramosetron or a pharmaceutically acceptable salt thereof, which is characterized by blending a compound having characteristics of absorbing light having a specific wavelength.
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申请公布号 |
EP2062579(A1) |
申请公布日期 |
2009.05.27 |
申请号 |
EP20070807115 |
申请日期 |
2007.09.12 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
UMEJIMA, HIROYUKI;KURIMOTO, IPPEI;KANBAYASHI, ATSUSHI;MORI, CHIEKO |
分类号 |
A61K31/4184;A61K9/16;A61K9/20;A61K47/02;A61K47/20;A61K47/26;A61P1/00;A61P1/08 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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