| 发明名称 |
Benzylether amine compounds usefl as CCR-5 antagonists |
| 摘要 |
The present invention relates to compounds which are CCR-5 receptor antagonists of the general formula I: wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>a</SUP>, R<SUP>b</SUP>, R<SUP>c</SUP>, R<SUP>d</SUP>, X, m and n are as defined herein. The invention further comprises pharmaeceutical compositions comprising such compounds, as well as the use of such compounds to treat CCR-5 mediated disorders. |
| 申请公布号 |
ZA200604788(B) |
申请公布日期 |
2009.05.27 |
| 申请号 |
ZA20060004788 |
申请日期 |
2006.06.09 |
| 申请人 |
SCHERING AKTIENGESELLSCHAFT |
发明人 |
DAVEY, DAVID;LU, SHOU-FU;WEI, GUO PING;LEE, WHEESEONG;PHILLIPS, GARY;YE, BIN |
| 分类号 |
A61K31/135;A61K31/165;A61K31/40;A61K31/435;C07C217/58;C07C235/42;C07C255/54;C07C275/28;C07D;C07D207/08;C07D207/12;C07D207/14;C07D207/16;C07D211/14;C07D211/26;C07D211/38;C07D211/42;C07D211/44;C07D211/46;C07D211/48;C07D211/52;C07D211/58;C07D211/62;C07D211/64;C07D211/66;C07D213/20;C07D213/30;C07D213/40;C07D213/53;C07D213/64;C07D213/82;C07D213/89;C07D217/06;C07D233/54;C07D233/88;C07D235/26;C07D241/08;C07D295/13;C07D295/192;C07D295/215;C07D295/26;C07D319/08;C07D333/34;C07D401/06;C07D401/12;C07D403/12;C07D405/12;C07D471/10;C07D487/08;C07D491/10 |
主分类号 |
A61K31/135 |
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